Development of a homogeneous screening assay for automated detection of antiviral agents active against severe acute respiratory syndrome-associated coronavirus
T Ivens, C Van den Eynde, K Van Acker, E Nijs… - Journal of virological …, 2005 - Elsevier
The severity and global spread of the 2003 outbreak of the severe acute respiratory
syndrome-associated coronavirus (SARS-CoV) highlighted the risks to human health posed
by emerging viral diseases and emphasized the need for specific therapeutic agents instead
of relying on existing broadly active antiviral compounds. The development of rapid
screening assays is essential for antiviral drug discovery. Thus, a screening system for anti-
SARS-CoV agents was developed, which evaluated compound potency, specificity and …
syndrome-associated coronavirus (SARS-CoV) highlighted the risks to human health posed
by emerging viral diseases and emphasized the need for specific therapeutic agents instead
of relying on existing broadly active antiviral compounds. The development of rapid
screening assays is essential for antiviral drug discovery. Thus, a screening system for anti-
SARS-CoV agents was developed, which evaluated compound potency, specificity and …