The diabetes control and complications trial--implications for policy and practice

RD Lasker - New England Journal of Medicine, 1993 - Mass Medical Soc
RD Lasker
New England Journal of Medicine, 1993Mass Medical Soc
The results of the Diabetes Control and Complications Trial (DCCT), published in this issue
of the Journal, 1 demonstrate that intensive insulin therapy can delay the onset and slow the
progression of retinopathy, nephropathy, and neuropathy in patients with insulin-dependent
diabetes mellitus (IDDM). These findings, which extend those of two other recent studies, 2,
3 should put to rest the longstanding debate over whether attempts to improve glycemic
control beyond that required to control the symptoms of diabetes are worthwhile. But the …
The results of the Diabetes Control and Complications Trial (DCCT), published in this issue of the Journal,1 demonstrate that intensive insulin therapy can delay the onset and slow the progression of retinopathy, nephropathy, and neuropathy in patients with insulin-dependent diabetes mellitus (IDDM). These findings, which extend those of two other recent studies,2,3 should put to rest the longstanding debate over whether attempts to improve glycemic control beyond that required to control the symptoms of diabetes are worthwhile.
But the DCCT raises a new and equally challenging set of questions. The study was limited to a small subgroup of people . . .
The New England Journal Of Medicine