[HTML][HTML] Prognostic significance of progesterone receptor–positive tumor cells within immunohistochemically defined luminal A breast cancer

A Prat, MCU Cheang, M Martín, JS Parker… - Journal of clinical …, 2013 - ncbi.nlm.nih.gov
A Prat, MCU Cheang, M Martín, JS Parker, E Carrasco, R Caballero, S Tyldesley, K Gelmon…
Journal of clinical oncology, 2013ncbi.nlm.nih.gov
Purpose Current immunohistochemical (IHC)-based definitions of luminal A and B breast
cancers are imperfect when compared with multigene expression-based assays. In this
study, we sought to improve the IHC subtyping by examining the pathologic and gene
expression characteristics of genomically defined luminal A and B subtypes.
Abstract
Purpose
Current immunohistochemical (IHC)-based definitions of luminal A and B breast cancers are imperfect when compared with multigene expression-based assays. In this study, we sought to improve the IHC subtyping by examining the pathologic and gene expression characteristics of genomically defined luminal A and B subtypes.
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