[PDF][PDF] The failure of immunosuppression withdrawal: patient benefit is not detectable, inducible, or reproducible

P Porrett, A Shaked - Liver Transplantation, 2011 - Wiley Online Library
P Porrett, A Shaked
Liver Transplantation, 2011Wiley Online Library
Abstract Key Points (1) Immunosuppression is responsible for excellent patient outcomes.(2)
Immunosuppression withdrawal fails in most patients.(3) Patients who may benefit from
immunosuppression withdrawal cannot currently be identified.(4) No data suggest that
immunosuppression withdrawal decreases patient morbidity (ie, nephrotoxicity).(5) The
minimization of immunosuppression instead of withdrawal may be adequate for improving
patient outcomes. Liver Transpl, 2011.© 2011 AASLD.
Abstract
Key Points
(1) Immunosuppression is responsible for excellent patient outcomes.
(2) Immunosuppression withdrawal fails in most patients.
(3) Patients who may benefit from immunosuppression withdrawal cannot currently be identified.
(4) No data suggest that immunosuppression withdrawal decreases patient morbidity (ie, nephrotoxicity).
(5) The minimization of immunosuppression instead of withdrawal may be adequate for improving patient outcomes. Liver Transpl, 2011. © 2011 AASLD.
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