Morphological changes and alterations in regional intrarenal blood flow induced by graded renal ischemia
K Moran, J Mulhall, D Kelly, S Sheehan, J Dowsett… - The Journal of …, 1992 - Elsevier
A model of renal ischemia was used to study morphological changes and alterations in
intrarenal blood flow. Renal artery blood flow was reduced from 120 to 20 ml./minute
(normal 172±14) for 3 weeks. Morphological changes were assessed histologically, and by
electronmicroscopy. Intrarenal blood flow was determined using microspheres. Flow rates
less than 80 ml./minute resulted in a progressive loss of renal volume with arterial
thrombosis and renal infarction at 20 ml./minute. Histological changes included loss of …
intrarenal blood flow. Renal artery blood flow was reduced from 120 to 20 ml./minute
(normal 172±14) for 3 weeks. Morphological changes were assessed histologically, and by
electronmicroscopy. Intrarenal blood flow was determined using microspheres. Flow rates
less than 80 ml./minute resulted in a progressive loss of renal volume with arterial
thrombosis and renal infarction at 20 ml./minute. Histological changes included loss of …