Altered expression of regulators of the cortical chloride transporters NKCC1 and KCC2 in schizophrenia
D Arion, DA Lewis - Archives of general psychiatry, 2011 - jamanetwork.com
Objective: To compare the levels of NKCC1, KCC2, OXSR1, STK39, WNK1, WNK3, and
WNK4 transcripts in prefrontal cortex area 9 between subjects with schizophrenia and
healthy comparison subjects. Design: Real-time quantitative polymerase chain reaction
technique was used to measure transcript levels in the prefrontal cortex. Setting: Human
brain specimens were obtained from autopsies conducted at the Allegheny County Medical
Examiner's Office, Pittsburgh, Pennsylvania. Participants: Postmortem brain specimens from …
WNK4 transcripts in prefrontal cortex area 9 between subjects with schizophrenia and
healthy comparison subjects. Design: Real-time quantitative polymerase chain reaction
technique was used to measure transcript levels in the prefrontal cortex. Setting: Human
brain specimens were obtained from autopsies conducted at the Allegheny County Medical
Examiner's Office, Pittsburgh, Pennsylvania. Participants: Postmortem brain specimens from …