Profile of gene expression in a murine model of allergic bronchopulmonary aspergillosis
VP Kurup, R Raju, P Manickam - Infection and immunity, 2005 - Am Soc Microbiol
VP Kurup, R Raju, P Manickam
Infection and immunity, 2005•Am Soc MicrobiolAllergic bronchopulmonary aspergillosis (ABPA) results from the interactions of the
Aspergillus allergens and immune system of the patients. We studied the gene expression
profile in a mouse model of ABPA. Of the 12,000 genes studied, 1,300 genes showed
enhanced expression and represent chemokine, cytokine, growth factor, signal transduction,
and transmembrane receptor genes as well as genes related to arginine metabolism.
Aspergillus allergens and immune system of the patients. We studied the gene expression
profile in a mouse model of ABPA. Of the 12,000 genes studied, 1,300 genes showed
enhanced expression and represent chemokine, cytokine, growth factor, signal transduction,
and transmembrane receptor genes as well as genes related to arginine metabolism.
Abstract
Allergic bronchopulmonary aspergillosis (ABPA) results from the interactions of the Aspergillus allergens and immune system of the patients. We studied the gene expression profile in a mouse model of ABPA. Of the 12,000 genes studied, 1,300 genes showed enhanced expression and represent chemokine, cytokine, growth factor, signal transduction, and transmembrane receptor genes as well as genes related to arginine metabolism.
American Society for Microbiology