Evidence that glutamate is released from capsaicin-sensitive primary afferent fibers in rats: study with on-line continuous monitoring of glutamate
M Ueda, Y Kuraishi, K Sugimoto, M Satoh - Neuroscience research, 1994 - Elsevier
The aim of this study is to elucidate whether the excitatory amino acid glutamate is released
from capsaicin-sensitive primary afferent fibers, and to compare the releasing effect of
capsaicin on glutamate with that on substance P. The release of glutamate was measured
using a fluorometric on-line continuous monitoring system, in which the immobilized
glutamate dehydrogenase column was connected to an in vitro superfusion system. In the
presence of 0.3 μM tetrodotoxin, 2-min application of capsaicin produced an increased …
from capsaicin-sensitive primary afferent fibers, and to compare the releasing effect of
capsaicin on glutamate with that on substance P. The release of glutamate was measured
using a fluorometric on-line continuous monitoring system, in which the immobilized
glutamate dehydrogenase column was connected to an in vitro superfusion system. In the
presence of 0.3 μM tetrodotoxin, 2-min application of capsaicin produced an increased …