Effect of interleukin 2 on intractable herpes virus infection and chronic eczematoid dermatitis in a patient with Wiskott-Aldrich syndrome

H Azuma, H Sakata, M Saijyou, A Okuno - European journal of pediatrics, 1993 - Springer
H Azuma, H Sakata, M Saijyou, A Okuno
European journal of pediatrics, 1993Springer
Abstract Recombinant interleukin 2 (rIL2) was administered to a patient with Wiskott-Aldrich
syndrome for the treatment of an intractabel facial herpetiforme lesion. This treatment
appeared to be effective in suppressing the virus activity. At the same time, a transient
improvement of the chronic eczematoid dermatitis was observed. During rIL2 administration,
the CD3+ and CD4+ subsets of peripheral blood lymphocytes increased in number. These
changes might play an important role in the induction of anti-viral immunity and in the …
Abstract
Recombinant interleukin 2 (rIL2) was administered to a patient with Wiskott-Aldrich syndrome for the treatment of an intractabel facial herpetiforme lesion. This treatment appeared to be effective in suppressing the virus activity. At the same time, a transient improvement of the chronic eczematoid dermatitis was observed. During rIL2 administration, the CD3+ and CD4+ subsets of peripheral blood lymphocytes increased in number. These changes might play an important role in the induction of anti-viral immunity and in the improvement of dermatits.
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