Invariant NKT and NKT-like lymphocytes: two different T cell subsets that are differentially affected by ageing
E Peralbo, C Alonso, R Solana - Experimental gerontology, 2007 - Elsevier
The expression on T lymphocytes of surface receptors that are characteristically expressed
on NK cells has led to the definition of a T cell subset that has been termed Natural Killer T
(NKT) cells. Thus NKT cells constitute a minor lymphocyte population that exhibits features
of both T cells and NK cells. However, the term 'NKT cell'has been applied variably to cells
that express a restricted T-cell receptor (TCR) that recognizes glycolipids (α-GalCer)
presented by the MHC-like molecule CD1d and that express CD161, as well as populations …
on NK cells has led to the definition of a T cell subset that has been termed Natural Killer T
(NKT) cells. Thus NKT cells constitute a minor lymphocyte population that exhibits features
of both T cells and NK cells. However, the term 'NKT cell'has been applied variably to cells
that express a restricted T-cell receptor (TCR) that recognizes glycolipids (α-GalCer)
presented by the MHC-like molecule CD1d and that express CD161, as well as populations …