[HTML][HTML] A spatial approach to transcriptional profiling: mechanotransduction and the focal origin of atherosclerosis
PF Davies, DC Polacek, JS Handen, BP Helmke… - Trends in …, 1999 - cell.com
PF Davies, DC Polacek, JS Handen, BP Helmke, N DePaola
Trends in biotechnology, 1999•cell.comThe initiation and progression of focal atherosclerotic lesions has long been known to be
associated with regions of disturbed blood flow. Improved precision in experimental models
of spatially defined flow has recently been combined with regional and single-cell gene-
expression profiling to investigate the relationships linking haemodynamics to vessel-wall
pathobiology.
associated with regions of disturbed blood flow. Improved precision in experimental models
of spatially defined flow has recently been combined with regional and single-cell gene-
expression profiling to investigate the relationships linking haemodynamics to vessel-wall
pathobiology.
Abstract
The initiation and progression of focal atherosclerotic lesions has long been known to be associated with regions of disturbed blood flow. Improved precision in experimental models of spatially defined flow has recently been combined with regional and single-cell gene-expression profiling to investigate the relationships linking haemodynamics to vessel-wall pathobiology.
cell.com