The hematopoietic system generally has reserve sufficient to tolerate significant insult and
regenerative capacity to overcome most damage due to infectious agents. However, HIV
infection results in a progressive decline in hematopoietic function and even in the context of
potent, anti-retroviral therapy is able to only incompletely reconstitute immune function. The
ability of the immune system to respond to HIV itself remains compromised, a defect that
leaves infected individuals with a lifelong dependence on medications. The capability of …