[HTML][HTML] The heterogeneous nuclear ribonucleoprotein L is an essential component in the Ca2+/calmodulin-dependent protein kinase IV-regulated alternative splicing …
J Yu, Y Hai, G Liu, T Fang, SKP Kung, J Xie - Journal of biological chemistry, 2009 - ASBMB
The regulation of gene expression through alternative pre-mRNA splicing is common in
metazoans and is often controlled by intracellular signaling pathways that are important in
cell physiology. We have shown that the alternative splicing of a number of genes is
controlled by membrane depolarization and Ca 2+/calmodulin-dependent protein kinase IV
(CaMKIV) through CaMKIV-responsive RNA elements (CaRRE1 and CaRRE2); however,
the trans-acting factors remain unknown. Here we show that the heterogeneous nuclear …
metazoans and is often controlled by intracellular signaling pathways that are important in
cell physiology. We have shown that the alternative splicing of a number of genes is
controlled by membrane depolarization and Ca 2+/calmodulin-dependent protein kinase IV
(CaMKIV) through CaMKIV-responsive RNA elements (CaRRE1 and CaRRE2); however,
the trans-acting factors remain unknown. Here we show that the heterogeneous nuclear …