[HTML][HTML] Regulatory sequences of the mouse villin gene that efficiently drive transgenic expression in immature and differentiated epithelial cells of small and large …
D Pinto, S Robine, F Jaisser, F El Marjou… - Journal of Biological …, 1999 - ASBMB
Villin is an early marker of epithelial cells from the digestive and urogenital tracts. Indeed
villin is expressed in the stem cells and the proliferative cells of the intestinal crypts. To
investigate the underlying molecular mechanisms and particularly those responsible for the
restricted tissue specificity, a large genomic region of the mouse villin gene has been
analyzed. A 9-kilobase (kb) regulatory region of the mouse villin gene (harboring 3.5 kb
upstream the transcription start site and 5.5 kb of the first intron) was able to promote …
villin is expressed in the stem cells and the proliferative cells of the intestinal crypts. To
investigate the underlying molecular mechanisms and particularly those responsible for the
restricted tissue specificity, a large genomic region of the mouse villin gene has been
analyzed. A 9-kilobase (kb) regulatory region of the mouse villin gene (harboring 3.5 kb
upstream the transcription start site and 5.5 kb of the first intron) was able to promote …
