Prognostic value of placental growth factor in patients with acute chest pain

C Heeschen, S Dimmeler, S Fichtlscherer, CW Hamm… - Jama, 2004 - jamanetwork.com
ContextExperimental data suggest that placental growth factor (PlGF), a member of the
vascular endothelial growth factor family, acts as a primary inflammatory instigator of
atherosclerotic plaque instability and thus may be useful as a risk-predicting biomarker in
patients with acute coronary syndromes (ACS). ObjectiveTo determine whether blood levels
of PlGF predict risk for death or nonfatal myocardial infarction in patients with acute chest
pain. Design, Setting, and PatientsMeasurement of PlGF levels as well as levels of markers …