Triggering of the B cell antigen receptor (BCR) can initiate divergent reponses ranging from
activation and cell division to apoptosis, depending on the differentiation stage and
additional signals the cell receives. Despite considerable progress in unraveling general
apoptosis pathways, the route from the BCR to apoptosis execution is still quite obscure, and
there is no consensus yet concerning the mechanism or the players involved. Here, we will
summarize current developments in this field and will attempt to pinpoint key questions and …