[HTML][HTML] Bcl-2 proteins and apoptosis: choose your partner
GC Shore, M Nguyen - Cell, 2008 - cell.com
GC Shore, M Nguyen
Cell, 2008•cell.comThe Bcl-2 family protein Bax is a key effector of apoptosis. Lovell et al.(2008) now describe
the reconstitution and regulation in liposomes of tBid-mediated membrane penetration and
oligomerization of Bax. These and other recent studies shed new light on the control of
permeabilization of the mitochondrial outer membrane during apoptosis.
the reconstitution and regulation in liposomes of tBid-mediated membrane penetration and
oligomerization of Bax. These and other recent studies shed new light on the control of
permeabilization of the mitochondrial outer membrane during apoptosis.
The Bcl-2 family protein Bax is a key effector of apoptosis. Lovell et al. (2008) now describe the reconstitution and regulation in liposomes of tBid-mediated membrane penetration and oligomerization of Bax. These and other recent studies shed new light on the control of permeabilization of the mitochondrial outer membrane during apoptosis.
cell.com