Teleost introns are characterized by a high A+ T content
P Winnard, BD Sidell, ME Vayda - … and Physiology Part B: Biochemistry and …, 2002 - Elsevier
We previously observed that Antarctic fish genes contain intron sequences of high A+ T
content (60–70% average A+ T) which are in stark contrast with adjacent protein coding-
sequences. Here, we report that this disparity in intron/exon base composition is a common
feature among teleosts. We analyzed 483 teleost genomic DNA sequences, containing 2583
introns, from 80 teleost genera that populate polar, temperate, or tropical habitats. Eighty-
nine percent of teleost introns display an A+ T content between 50–84% A+ T with a mean of …
content (60–70% average A+ T) which are in stark contrast with adjacent protein coding-
sequences. Here, we report that this disparity in intron/exon base composition is a common
feature among teleosts. We analyzed 483 teleost genomic DNA sequences, containing 2583
introns, from 80 teleost genera that populate polar, temperate, or tropical habitats. Eighty-
nine percent of teleost introns display an A+ T content between 50–84% A+ T with a mean of …
