Overexpression of clusterin in transitional cell carcinoma of the bladder is related to disease progression and recurrence

H Miyake, M Gleave, S Kamidono, I Hara - Urology, 2002 - Elsevier
Objectives. To determine whether the expression level of clusterin in transitional cell
carcinoma (TCC) of the bladder could be used as a predictor of tumor recurrence and
prognosis. Methods. Total RNA samples were extracted from 89 specimens of TCC of the
bladder, and the expression level of clusterin mRNA in these specimens was measured by
Northern blot analysis. The results were evaluated with respect to several clinicopathologic
factors. Results. The mean level of clusterin mRNA expression in invasive TCC of the …