Dual promoter structure of mouse and human fatty acid translocase/CD36 genes and unique transcriptional activation by peroxisome proliferator-activated receptor α …
O Sato, C Kuriki, Y Fukui, K Motojima - Journal of Biological Chemistry, 2002 - ASBMB
Fatty acid translocase (FAT)/CD36 is a glycoprotein involved in multiple membrane functions
including uptake of long-chain fatty acids and oxidized low density lipoprotein. In mice,
expression of the gene is regulated by peroxisome proliferator-activated receptor (PPAR) α
in the liver and by PPARγ in the adipose tissues (Motojima, K., Passilly, PP, Peters, JM,
Gonzalez, FJ, and Latruffe, N.(1998) J. Biol. Chem. 273, 16710–16714). However, the time
course of PPARα ligand-induced expression of FAT/CD36 in the liver, and also in the …
including uptake of long-chain fatty acids and oxidized low density lipoprotein. In mice,
expression of the gene is regulated by peroxisome proliferator-activated receptor (PPAR) α
in the liver and by PPARγ in the adipose tissues (Motojima, K., Passilly, PP, Peters, JM,
Gonzalez, FJ, and Latruffe, N.(1998) J. Biol. Chem. 273, 16710–16714). However, the time
course of PPARα ligand-induced expression of FAT/CD36 in the liver, and also in the …
