Animal models of nonalcoholic fatty liver disease and steatohepatitis
AA Nanji - Clinics in liver disease, 2004 - liver.theclinics.com
Nonalcoholic fatty liver disease (NAFLD) is an increasingly recognized condition that may
progress to end-stage liver disease. It is characterized by its association with obesity,
diabetes, and hyperdyslipidemia. NAFLD refers to the wide spectrum of liver damage that
ranges from simple steatosis to steatohepatitis, advanced fibrosis, and cirrhosis [1–4]. As
occurs in people, NAFLD is associated strongly with obesity, diabetes, and dysplipidemia in
experimental animals. The reader is referred to previous work that reviews animal models of …
progress to end-stage liver disease. It is characterized by its association with obesity,
diabetes, and hyperdyslipidemia. NAFLD refers to the wide spectrum of liver damage that
ranges from simple steatosis to steatohepatitis, advanced fibrosis, and cirrhosis [1–4]. As
occurs in people, NAFLD is associated strongly with obesity, diabetes, and dysplipidemia in
experimental animals. The reader is referred to previous work that reviews animal models of …
