Differential volumetry of A, B and D cells in the pancreatic islets of diabetic and nondiabetic subjects

KEN Saito, N Yaginuma, T Takahashi - The Tohoku journal of …, 1979 - jstage.jst.go.jp
KEN Saito, N Yaginuma, T Takahashi
The Tohoku journal of experimental medicine, 1979jstage.jst.go.jp
MATERIALS AND METHODS The pancreases from 59 autopsy cases were submitted to the
histometrical treatments (Table 1). The series consists of 26 maturity-onset diabetics (MOD),
5 growth-onset diabetics (GOD) and 28 nondiabetics (ND). Since the cases are identical to
those used for islet morphometry in the foregoing study, the total islet volume Vi in each case
is already known (Saito et al. 1978b). The diagnosis of diabetes mellitus was made on the
basis of urinalysis, fasting blood sugar level (FBS) and 50 g oral glucose tolerance test …
MATERIALS AND METHODS
The pancreases from 59 autopsy cases were submitted to the histometrical treatments (Table 1). The series consists of 26 maturity-onset diabetics (MOD), 5 growth-onset diabetics (GOD) and 28 nondiabetics (ND). Since the cases are identical to those used for islet morphometry in the foregoing study, the total islet volume Vi in each case is already known (Saito et al. 1978b). The diagnosis of diabetes mellitus was made on the basis of urinalysis, fasting blood sugar level (FBS) and 50 g oral glucose tolerance test (GTT). The diabetic cases revealed varying degrees of carbohydrate intolerance, but none of them was proved to be chemical diabetic.
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