Association of the calpain-10 gene with type 2 diabetes mellitus in a Mexican population

L del Bosque-Plata, CA Aguilar-Salinas… - Molecular Genetics and …, 2004 - Elsevier
Variation in the calpain-10 gene (CAPN10) has been associated with risk of type 2 diabetes
in the Mexican American population of Starr County, Texas. We typed five polymorphisms in
the calpain-10 gene (SNP-43,-43,-63, and-110 and Indel-19) to test for association with type
2 diabetes in 248 individuals representative of the mestizo population of Mexico City and
Orizaba, Mexico including 134 patients with type 2 diabetes and 114 subjects with normal
fasting blood glucose levels. We found a significant difference in SNP-44 allele and …