Screening of SNPs at 18 positional candidate genes, located within the GD-1 locus on chromosome 14q23–q32, for susceptibility to Graves' disease: a TDT study
DA Chistiakov, KV Savost'anov, RI Turakulov - Molecular Genetics and …, 2004 - Elsevier
Graves' disease (GD) is a complex autoimmune thyroid disorder with a strong genetic
component. Genome-wide screens resolved several susceptibility loci that contribute to the
development of GD. One of the susceptibility loci (GD-1 locus) was mapped on chromosome
14q31. However, a susceptibility gene located within the GD-1 locus remains undefined.
Here we screen eighteen single nucleotide polymorphisms (SNPs), each is situated at a
corresponding positional candidate gene, located within the GD-1 susceptibility locus on …
component. Genome-wide screens resolved several susceptibility loci that contribute to the
development of GD. One of the susceptibility loci (GD-1 locus) was mapped on chromosome
14q31. However, a susceptibility gene located within the GD-1 locus remains undefined.
Here we screen eighteen single nucleotide polymorphisms (SNPs), each is situated at a
corresponding positional candidate gene, located within the GD-1 susceptibility locus on …