A randomized placebo-controlled comparative trial of gabapentin and propranolol in essential tremor

A Gironell, J Kulisevsky, M Barbanoj… - Archives of …, 1999 - jamanetwork.com
Background New medication is needed to treat essential tremor. Preliminary evidence
suggests that gabapentin may be effective in the treatment of this disorder. Objective To
study the effects of gabapentin in a comparative, double-blind, crossover, placebo-controlled
trial of patients who have essential tremor. Patients and Methods 16 patients with essential
tremor (6 with a new onset and 10 with a 2-week washout period of previous treatment with
propranolol hydrochloride) received gabapentin (Neurontin), 400 mg 3 times daily; …