Longitudinal changes in glucose metabolism during pregnancy in obese women with normal glucose tolerance and gestational diabetes mellitus

PM Catalano, L Huston, SB Amini, SC Kalhan - American journal of …, 1999 - Elsevier
Objective: This study prospectively evaluated the longitudinal changes in insulin sensitivity,
insulin response, and endogenous (primarily hepatic) glucose production and suppression
during insulin infusion in women with normal glucose tolerance (control) and gestational
diabetes mellitus before and during a planned pregnancy. Study Design: Eight control
subjects and 7 subjects in whom gestational diabetes mellitus developed were evaluated
with an oral glucose tolerance test, an intravenous glucose tolerance test, and …