T-cell anergy and altered T-cell receptor signaling: effects on autoimmune disease
KV Salojin, J Zhang, J Madrenas, TL Delovitch - Immunology Today, 1998 - cell.com
KV Salojin, J Zhang, J Madrenas, TL Delovitch
Immunology Today, 1998•cell.comImmunological self-tolerance can be acquired by several mechanisms, including the
induction of anergy in autoreactive T cells. In this sense, anergy is predictably advantageous
for the immune system. Here, Konstantin Salojin and colleagues present an alternative view
that the induction of anergy in regulatory T cells may be harmful to the host and elicit
autoimmune disease.
induction of anergy in autoreactive T cells. In this sense, anergy is predictably advantageous
for the immune system. Here, Konstantin Salojin and colleagues present an alternative view
that the induction of anergy in regulatory T cells may be harmful to the host and elicit
autoimmune disease.
Abstract
Immunological self-tolerance can be acquired by several mechanisms, including the induction of anergy in autoreactive T cells. In this sense, anergy is predictably advantageous for the immune system. Here, Konstantin Salojin and colleagues present an alternative view that the induction of anergy in regulatory T cells may be harmful to the host and elicit autoimmune disease.
cell.com
