RNAse protection assays for the simultaneous and semiquantitative analysis of multiple murine matrix metalloproteinase (MMP) and MMP inhibitor mRNAs
A Pagenstecher, AK Stalder, IL Campbell - Journal of immunological …, 1997 - Elsevier
Matrix metalloproteinases (MMPs) are a family of proteinases that play a major role in the
metabolic degradation of extracellular matrix proteins. In order to examine the expression
pattern of different MMP or MMP-inhibitor genes two RNase protection assays (RPAs) were
developed that allow the simultaneous and semiquantitative assessment of their respective
mRNAs. Probes for the detection of MMPs stromelysin 1, 2 and 3, matrilysin,
metalloelastase, gelatinase A and B, collagenase and membrane type MMP (MT1-MMP) …
metabolic degradation of extracellular matrix proteins. In order to examine the expression
pattern of different MMP or MMP-inhibitor genes two RNase protection assays (RPAs) were
developed that allow the simultaneous and semiquantitative assessment of their respective
mRNAs. Probes for the detection of MMPs stromelysin 1, 2 and 3, matrilysin,
metalloelastase, gelatinase A and B, collagenase and membrane type MMP (MT1-MMP) …
