Anatomy of viral persistence: mechanisms of persistence and associated disease
JC de la Torre, MBA Oldstone - Advances in virus research, 1996 - Elsevier
Publisher Summary The knowledge that viruses can persist is as important finding in
virology. Indeed, the puzzle for a virus to solve is how to live within a host over the lifetime of
the host. Viruses that persist in a host are ultimately successful by virtue of their abilities to
(1) survive within cells that provide their sustenance, and (2) avoid recognition by the host
immune system. Viruses that persist must remain within a cell for a prolonged time without
disturbing the transcription or translation of genes necessary for survival of the infected cell …
virology. Indeed, the puzzle for a virus to solve is how to live within a host over the lifetime of
the host. Viruses that persist in a host are ultimately successful by virtue of their abilities to
(1) survive within cells that provide their sustenance, and (2) avoid recognition by the host
immune system. Viruses that persist must remain within a cell for a prolonged time without
disturbing the transcription or translation of genes necessary for survival of the infected cell …
