Analysis of autoantibodies to T-cell receptors among HIV-infected individuals: epitope analysis and time course
JJ Marchalonis, NM Ampel, SF Schluter, A Garza… - Clinical immunology and …, 1997 - Elsevier
Individuals seropositive for human immunodeficiency virus type 1 (HIV) express elevated
levels of autoantibodies (AAbs) directed against recombinant T-cell receptors (TCRs) and
synthetic peptide epitopes duplicating β chain markers. We performed longitudinal studies of
anti-TCR AAbs in HIV-1-infected individuals, making comparisons with uninfected sera and
sera from other individuals infected with a nonviral agent. We determined levels of
autoantibodies by titration using enzyme-linked immunosorbent assay (ELISA) and …
levels of autoantibodies (AAbs) directed against recombinant T-cell receptors (TCRs) and
synthetic peptide epitopes duplicating β chain markers. We performed longitudinal studies of
anti-TCR AAbs in HIV-1-infected individuals, making comparisons with uninfected sera and
sera from other individuals infected with a nonviral agent. We determined levels of
autoantibodies by titration using enzyme-linked immunosorbent assay (ELISA) and …
