[HTML][HTML] Overexpression of the homeobox gene DLX-7 inhibits apoptosis by induced expression of intercellular adhesion molecule-1
T Shimamoto, K Ohyashiki, K Takeshita - Experimental Hematology, 2000 - Elsevier
OBJECTIVE: DLX genes constitute a subfamily of divergent homeobox genes. We have
previously reported that inhibition of DLX-7 expression by an antisense oligonucleotide
caused apoptosis in the K562 erythroleukemia cell line, which highly expresses DLX-7. In
this study, we have constructed an expression vector encoding human DLX-7, and
examined the effects of overexpression of DLX-7 in the IL-3-dependent lymphoid precursor
cell line Ba/F3. METHODS: DLX-7 expression vector was electroporated into Ba/F3 cells …
previously reported that inhibition of DLX-7 expression by an antisense oligonucleotide
caused apoptosis in the K562 erythroleukemia cell line, which highly expresses DLX-7. In
this study, we have constructed an expression vector encoding human DLX-7, and
examined the effects of overexpression of DLX-7 in the IL-3-dependent lymphoid precursor
cell line Ba/F3. METHODS: DLX-7 expression vector was electroporated into Ba/F3 cells …