Comparison between epidermal growth factor, transforming growth factor-α and EGF receptor levels in regions of adult rat brain
MR Kaser, J Lakshmanan, DA Fisher - Molecular brain research, 1992 - Elsevier
Examination of adult rat brain regions by specific radioimmunoassays revealed a
widespread distribution of transforming growth factor-α (TGF-α), but not epidermal growth
factor (EGF), the peptide that had previously been reported to be present in rodent brain.
Polyadenylated RNA samples from the different regions of rat brain were analyzed by
Northern blot to identify mRNA species encoding precursor proteins for EGF (preproEGF),
TGF-α (preproTGF-α), and the EGF/TGF-α receptor. The results indicate that TGF-α is the …
widespread distribution of transforming growth factor-α (TGF-α), but not epidermal growth
factor (EGF), the peptide that had previously been reported to be present in rodent brain.
Polyadenylated RNA samples from the different regions of rat brain were analyzed by
Northern blot to identify mRNA species encoding precursor proteins for EGF (preproEGF),
TGF-α (preproTGF-α), and the EGF/TGF-α receptor. The results indicate that TGF-α is the …