[HTML][HTML] Molecular cloning and characterization of human podocalyxin-like protein: orthologous relationship to rabbit PCLP1 and rat podocalyxin
DB Kershaw, SG Beck, BL Wharram, JE Wiggins… - Journal of Biological …, 1997 - ASBMB
Human renal cortex and heart cDNA libraries were screened for a human homolog of rabbit
PCLP1 using the rabbit PCLP1 cDNA as a probe. Clones spanning 5869 base pairs with an
open reading frame coding for a 528-amino acid peptide were obtained. The putative
peptide contains a potential signal peptide and a single membrane-spanning region. The
extracellular domain contains multiple potential sites for N-and O-linked glycosylation and 4
cysteines for potential disulfide bonding similar to rabbit PCLP1. On Northern blot a major …
PCLP1 using the rabbit PCLP1 cDNA as a probe. Clones spanning 5869 base pairs with an
open reading frame coding for a 528-amino acid peptide were obtained. The putative
peptide contains a potential signal peptide and a single membrane-spanning region. The
extracellular domain contains multiple potential sites for N-and O-linked glycosylation and 4
cysteines for potential disulfide bonding similar to rabbit PCLP1. On Northern blot a major …