T cell co-stimulatory molecules other than CD28.
TH Watts, MA DeBenedette - Current opinion in immunology, 1999 - europepmc.org
TH Watts, MA DeBenedette
Current opinion in immunology, 1999•europepmc.orgCD28 is the primary co-stimulatory receptor for inducing high-level IL-2 production and
survival of naïve CD4 (+) T cells. While no other cell surface receptor can be considered fully
redundant with CD28, recent developments suggest that additional co-stimulatory pathways
have preferential effects at different stages of T cell activation, on different subsets of T cells
or contribute to the development of different effector functions.
survival of naïve CD4 (+) T cells. While no other cell surface receptor can be considered fully
redundant with CD28, recent developments suggest that additional co-stimulatory pathways
have preferential effects at different stages of T cell activation, on different subsets of T cells
or contribute to the development of different effector functions.
CD28 is the primary co-stimulatory receptor for inducing high-level IL-2 production and survival of naïve CD4 (+) T cells. While no other cell surface receptor can be considered fully redundant with CD28, recent developments suggest that additional co-stimulatory pathways have preferential effects at different stages of T cell activation, on different subsets of T cells or contribute to the development of different effector functions.
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