Pathophysiology of asthma

PJ Barnes, JM Drazen - Asthma and COPD, 2002 - Elsevier
Publisher Summary Asthma and chronic obstructive pulmonary disease (COPD) are highly
complex airway-obstruction disease conditions. Chronic inflammation of airways is
recognized as one of the major causes of both asthma and COPD. Inflammation in asthmatic
airways not only involves the trachea and bronchi but also extends to the terminal
bronchioles and parenchyma. Inflammation needs to reach a certain threshold to result in
symptoms. The degree of inflammation does not relate to asthma severity but relates to …